Baywood's
Diosmin Caps combine Diosmin and Hesperidin to make
the most complete, effective combination formula
for supporting healthy veins. Diosmin and Hesperidin
are two natural citrus bioflavonoids. Both have
anti-inflammatory and antioxidant activity and support
over-all cardiovascular health, in addition to the
cosmetic benefits of reducing the appearance of
varicose veins and spider veins.
Diosmin
and Hesperidin are used widely in Europe for decreasing
the appearance of varicose veins and spider veins,
and also hemmorhoids. Hesperidin is the predominant
flavonoid in lemons and oranges. The peel and membranous
parts of these fruits have the highest hesperidin
concentrations. Hesperidin is classified as a citrus
bioflavonoid. Hesperidin, Diosmin and other flavonoids
thought to reduce capillary permeability and to
have anti-inflammatory action were collectively
known as vitamin P. These substances, however, are
not vitamins and are no longer referred to, except
in older literature, as vitamin P.
Like
almost everything else in our bodies, our veins
are susceptible to deterioration with age, especially
if we have a poor diet or inadequate exercise. This
is particularly true of the veins in our legs, which
have the difficult job of conducting blood upward
against gravity's relentless pull. The movements
of the legs act as a pump to push the blood upward
while flimsy valves stop gravity from pulling it
back down. However, over time these valves often
begin to fail and the blood then begins to pool
in the deep veins of the leg, stretching the vein
wall and injuring its lining. This situation is
called venous insufficiency.
What
are Varicose Veins?
Varicose
veins, a condition closely related to venous insufficiency,
occur when veins near the surface of the skin
are damaged. They visibly dilate and become distorted,
resulting in a cosmetically unpleasant appearance
resulting in varicose veins and hemorrhoids (actually,
the latter are varicose veins, just in a different
place), which afflict countless millions of people,
especially in Western societies, where the incidence
is believed to be about 50% of all people over
50 years of age. Researchers aren't completely
sure why some veins become varicose. Heredity
is believed to play a part, as are hormones. That's
one of the reasons varicose veins may be more
common in pregnancy.
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In
one study, distended veins improved considerably within
only 60 minutes, and the effect was still prominent
four hours later (Struckmann 1994). In addition, a
Danish study showed that these amazing flavonoids
were able to improve the elasticity of veins as well
as help the capillaries by reducing permeability and
leakage and support circulation (Struckmann 1999).
In
Italy, a 42-day study was conducted with 40 people
suffering from lower-limb circulation problems due
to unstable blood sugar levels. Researchers measured
the impact of hesperidin and diosmin on capillary
filtration of albumin, a specific protein retention
and filtration problem common among those with imbalanced
blood sugar. Results showed that 55% of those taking
the flavonoids achieved completely normal capillary
filtration of albumin: a remarkable success in fewer
than 45 days (Valensi 1996).
London
researchers evaluated the effects of diosmin and hesperidin
on 25 people who had lost normal elasticity in their
leg veins. In just four weeks, those who received
the nutrients demonstrated increased elasticity of
their leg veins, healthy blood flow, and stronger
venous structure (Ibegbuna 1997).
In
yet another study, people at high risk of forming
traveling blood clots were given hesperidin and diosmin
both before and after undergoing major surgery. The
injection of flavonoids dramatically reduced their
risk compared with those who received a placebo (Tsimoyiannis
1996).
References
Ibegbuna, V. et al. (1997). “Venous elasticity
after treatment with Daflon 500 mg.” Angiology;
48(1): 45-9.
Moore, D. (2002). “Fast facts: Blood clots.”
March 18: www.drdonnica.com/display.asp?article=4671.
Struckmann, J.R. & Nicolaides, A.N. (1994). “Flavonoids:
A review of the pharmacology and therapeutic efficacy
of Daflon 500 mg in patients with chronic venous insufficiency
and related disorders.” Angiology; 45(6): 419-28.
Struckmann, J.R. (1999). “Clinical efficacy
of micronized purified flavonoid fraction: An overview.”
Journal of Vascular Research; 36(Suppl 1): 37-41.
Tsimoyiannis, E.C. et al. (1996). “Low-molecular-weight
heparins and Daflon for prevention of postoperative
thromboembolism.” World Journal of Surgery;
20(8): 968-72.
Valensi, P.E. et al. (1996). “Effects of a purified
micronized flavonoid fraction on capillary filtration
in diabetic patients.” Diabetic Medicine; 13(10):
882-8.
*These
statements have not been evaluated by the Food and
Drug Administration(FDA). This product is not intended
to diagnose, treat, cure or prevent any disease
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